BDBM611765 1-benzyl-N-(3-chloro-2- fluoro-4-methoxy- phenyl)-1H-1,2,4- triazole-3-carboxamide::US11718612, Example 30

SMILES COc1ccc(NC(=O)c2ncn(Cc3ccccc3)n2)c(F)c1Cl

InChI Key InChIKey=DTAPMMZVGGTJSB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611765   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University Of Texas

US Patent
LigandPNGBDBM611765(US11718612, Example 30 | 1-benzyl-N-(3-chloro-2- f...)
Affinity DataIC50: 110nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
Go to US Patent