BDBM611728 US11718612, Example 1

SMILES Fc1cccc(Cn2nc3c(CCN(C3=O)c3cccc(Cl)c3F)c2Cl)c1F

InChI Key InChIKey=PCHFPQUTJXANGZ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611728   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University Of Texas

US Patent

LigandBDBM611728(US11718612, Example 1)Copy SMILESCopy InChI

Affinity DataIC50: 13.1nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/15/2023
Entry Details
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