BDBM61119 2-Chloro-1-(8-methyl-1,2,3a,4,5,6-hexahydro-pyrazino[3,2,1-jk]carbazol-3-yl)-ethanone::MLS001211906::SMR000516551::cid_3129074

SMILES Cc1ccc2n3CCN(C4CCCc(c34)c2c1)C(=O)CCl

InChI Key InChIKey=GFAMGQKPRPMKPF-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 61119   

TargetG-protein coupled receptor 55(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61119(2-Chloro-1-(8-methyl-1,2,3a,4,5,6-hexahydro-pyrazi...)
Affinity DataEC50:  3.20E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM61119(2-Chloro-1-(8-methyl-1,2,3a,4,5,6-hexahydro-pyrazi...)
Affinity DataIC50: 1.39E+3nMAssay Description:Southern Research's Specialized Biocontainment Screening Center (SRSBSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Librarie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Indiana University School of Medicine 635 Barnhill Drive

Curated by ChEMBL
LigandPNGBDBM61119(2-Chloro-1-(8-methyl-1,2,3a,4,5,6-hexahydro-pyrazi...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of GST-tagged TEAD4 (217 to 434 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed