BDBM611149 (2S)-N-[[3-[(4- cyanophenyl)methoxy]- 5-fluoro- phenyl]methyl]-1-(5- fluorobenzofuran-2-yl) sulfonyl-pyrrolidine-2- carboxamide::US10626112, Example 36

SMILES Fc1cc(CNC(=O)C2CCCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cc(OCc2ccc(cc2)C#N)c1

InChI Key InChIKey=KQANNKJNHLGJRZ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611149   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Ea Pharma

US Patent

LigandBDBM611149((2S)-N-[[3-[(4- cyanophenyl)methoxy]- 5-fluoro- ph...)Copy SMILESCopy InChI

Affinity DataIC50: 1.5nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/8/2023
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL