BDBM610898 US10626096, Example 11::[2-({[4-(2,6-Dimethoxyphenyl)-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)-7-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

SMILES COc1cccc(OC)c1-n1c(SCc2cc(=O)n3cc(C)ccc3n2)nnc1-c1cccs1

InChI Key InChIKey=QSRWQMLRJXASDN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 610898   

TargetApelin(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM610898(US10626096, Example 11 | [2-({[4-(2,6-Dimethoxyphe...)
Affinity DataEC50:  5nMAssay Description:The apelin receptor agonist activity of the compound represented by formula (I) or (II) of the present invention was measured by cell-based assay for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
Go to US Patent