BDBM6104 4-[(2,4-Dimethylphenyl)amino]-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinoline-3-carbonitrile::4-phenylamino-3-quinolinecarbonitrile 22

SMILES COc1cc2c(Nc3ccc(C)cc3C)c(cnc2cc1OCC1CCN(C)CC1)C#N

InChI Key InChIKey=YCFQNCQMGGRGHM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 6104   

LigandPNGBDBM6104(4-[(2,4-Dimethylphenyl)amino]-6-methoxy-7-[(1-meth...)
Affinity DataIC50: 63nMAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Wyeth Research

LigandPNGBDBM6104(4-[(2,4-Dimethylphenyl)amino]-6-methoxy-7-[(1-meth...)
Affinity DataIC50: 38nMAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6104(4-[(2,4-Dimethylphenyl)amino]-6-methoxy-7-[(1-meth...)
Affinity DataIC50: 38nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandPNGBDBM6104(4-[(2,4-Dimethylphenyl)amino]-6-methoxy-7-[(1-meth...)
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed