BDBM609996 1-(3-Chloro-2-fluorobenzyl)-4-(5-(6-hydroxy-1,4-oxazepan-4-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2(1H)-one::US11708364, Example 120

SMILES OC1COCCN(C1)c1cnc2[nH]cc(-c3ccn(Cc4cccc(Cl)c4F)c(=O)c3)c2c1

InChI Key InChIKey=CZCANHMGMYUZTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 609996   

TargetMitogen-activated protein kinase 1(Human)
Agv Discovery

US Patent
LigandPNGBDBM609996(US11708364, Example 120 | 1-(3-Chloro-2-fluorobenz...)
Affinity DataIC50: 10nMAssay Description:To assess compounds capacity to inhibit ERK2 enzymatic activity, Z′-Lyte biochemical assay from Life technologies was used according to manufac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent