BDBM609895 US11708366, Example 8

SMILES Fc1cc(ccc1Cl)N1C(=O)CCCC11CCN(CC1)c1nc(nnc1Cl)N1CCCC1

InChI Key InChIKey=PKSMRBWNQHUTFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 609895   

TargetLeukotriene C4 synthase(Human)
Novartis

US Patent
LigandPNGBDBM609895(US11708366, Example 8)
Affinity DataIC50: 7.00E+3nMAssay Description:LTC4 synthase catalyzes the conversion of Leukotriene A4(LTA4) to Leukotriene C4 (LTC4) in the presence of reduced glutathione (GSH) as a co-substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent