BDBM609841 2-(2-(2-(3-(aminomethyl)phenyl)-7-(pyrrolidin-1-ylmethyl)pyrrolo[2,1-f][1,2,4]triazine-4-carboxamido)phenyl)acetic Acid::US11708347, Compound 46g

SMILES NCc1cccc(c1)-c1nc(C(=O)Nc2ccccc2CC(O)=O)c2ccc(CN3CCCC3)n2n1

InChI Key InChIKey=AZFVXYLDSVHSNT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 609841   

TargetComplement factor D(Human)
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM609841(US11708347, Compound 46g | 2-(2-(2-(3-(aminomethyl...)
Affinity DataIC50: 5.50E+3nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used. For this assay Z-Lys-SBzl, 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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