BDBM60962 hCA inhibitor, 2

SMILES CCOC1Oc2c(F)cccc2C(=O)\C1=C/Nc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=UDHSGWXLHMTGFL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 60962   

TargetCarbonic anhydrase 2(Human)
Ondokuz Mayis University

LigandPNGBDBM60962(hCA inhibitor, 2)
Affinity DataKi:  437nM ΔG°:  -8.67kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ondokuz Mayis University

LigandPNGBDBM60962(hCA inhibitor, 2)
Affinity DataKi:  1.53E+3nM ΔG°:  -7.93kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM60962(hCA inhibitor, 2)
Affinity DataKi:  3.72E+4nM ΔG°:  -6.04kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed