BDBM60954 US9334268, 1-[2-(2-Aminoethoxy)ethyl]-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-4-amine

SMILES CCOCc1nc2c(N)nc3ccccc3c2n1CCOCCN

InChI Key InChIKey=KSUPHFQGJASHRU-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 60954   

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM60954(US9334268, 1-[2-(2-Aminoethoxy)ethyl]-2-(ethoxymet...)
Affinity DataEC50:  4.90E+4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2017
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM60954(US9334268, 1-[2-(2-Aminoethoxy)ethyl]-2-(ethoxymet...)
Affinity DataEC50: >1.00E+5nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2017
Entry Details
Go to US Patent