BDBM60947 BDBM50443972::US9247759, compound C

SMILES COc1ccc(CN(Cc2ccccc2)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1

InChI Key InChIKey=MOCKCIARDSIELI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 60947   

TargetTaste receptor type 2 member 14(Human)
Senomyx

US Patent
LigandPNGBDBM60947(US9247759, compound C | BDBM50443972)
Affinity DataIC50: 200nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

TargetTaste receptor type 2 member 14(Human)
Senomyx

US Patent
LigandPNGBDBM60947(US9247759, compound C | BDBM50443972)
Affinity DataIC50: 220nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

TargetTaste receptor type 2 member 8(Human)
Senomyx

US Patent
LigandPNGBDBM60947(US9247759, compound C | BDBM50443972)
Affinity DataIC50: 200nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

TargetProstaglandin E synthase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM60947(US9247759, compound C | BDBM50443972)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of mPGES-1 in human HeLa cells using PGH2 as substrate assessed as inhibition of IL-1beta/TNFalpha-stimulated PGE2 production preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed