BDBM609245 7-(5-(5-((3S,4S)-3-fluoro-4-hydroxy-4-methylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl)-4-((tetrahydro-2H-pyran-4-yl)amino)pyridin-2-yl)pyrrolo[1,2-b]pyridazine-3-carbonitrile::US11702414, Example 204

SMILES C[C@]1(O)CCN(C[C@@H]1F)c1nnc(s1)-c1cnc(cc1NC1CCOCC1)-c1ccc2cc(cnn12)C#N

InChI Key InChIKey=YFSIXAIRHOLUHP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 609245   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM609245(US11702414, Example 204 | 7-(5-(5-((3S,4S)-3-fluor...)
Affinity DataIC50: 350nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
Go to US Patent