BDBM609079 US11702414, Example 23::methyl (((1R,3r)- 3-((5-(5- ((1r,4R)-4- acetamidocyclohexyl)- 1,3,4-thiadiazol- 2-yl)-2-(3- cyanopyrrolo[1,2- b]pyridazin-7-yl) pyridin-4- yl)amino)cyclobutyl) methyl)carbamate

SMILES COC(=O)NC[C@H]1C[C@@H](C1)Nc1cc(ncc1-c1nnc(s1)[C@H]1CC[C@@H](CC1)NC(C)=O)-c1ccc2cc(cnn12)C#N

InChI Key InChIKey=YWQZYKMFSCLYKI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 609079   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM609079(US11702414, Example 23 | methyl (((1R,3r)- 3-((5-(...)
Affinity DataIC50: 1nMAssay Description:IRAK4 enzyme (Carna Biosciences, Chuo-ku, Kobe, Japan) activity was measured by detecting phosphorylated peptide substrate formation using an antibod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
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