BDBM609077 N-((1r,4r)- 4-(5-(6-(3- cyanopyrrolo[1,2- b]pyridazin-7-yl)- 4-(oxetan- 3-ylamino)pyridin- 3-yl)- 1,3,4-thiadiazol-2- yl)cyclohexyl) acetamide::US11702414, Example 21

SMILES CC(=O)N[C@H]1CC[C@@H](CC1)c1nnc(s1)-c1cnc(cc1NC1COC1)-c1ccc2cc(cnn12)C#N

InChI Key InChIKey=DGDLEHPAPBNOHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 609077   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM609077(US11702414, Example 21 | N-((1r,4r)- 4-(5-(6-(3- c...)
Affinity DataIC50: 1nMAssay Description:IRAK4 enzyme (Carna Biosciences, Chuo-ku, Kobe, Japan) activity was measured by detecting phosphorylated peptide substrate formation using an antibod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
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