BDBM609070 (R)-5-(6-(3- cyanopyrrolo[1,2- b]pyridazin-7-yl)-4- (isopropylamino) pyridin-3- yl)-N-(2-fluoro- 3-hydroxy- 3-methylbutyl)-1,3,4- thiadiazole- 2-carboxamide::US11702414, Example 14

SMILES CC(C)Nc1cc(ncc1-c1nnc(s1)C(=O)NC[C@@H](F)C(C)(C)O)-c1ccc2cc(cnn12)C#N

InChI Key InChIKey=KVVGKLQIJBKDRV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 609070   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM609070(US11702414, Example 14 | (R)-5-(6-(3- cyanopyrrolo...)
Affinity DataIC50: 1nMAssay Description:IRAK4 enzyme (Carna Biosciences, Chuo-ku, Kobe, Japan) activity was measured by detecting phosphorylated peptide substrate formation using an antibod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
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