BDBM6088 7-[(2,4-Dichloro-5-methoxyphenyl)amino]-2-{5-[(4-methylpiperazin-1-yl)methyl]thien-3-yl}thieno[3,2-b]pyridine-6-carbonitrile::7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-{5-[(4-methylpiperazin-1-yl)methyl]thiophen-3-yl}thieno[3,2-b]pyridine-6-carbonitrile::7-phenylaminothieno[3,2-b]pyridine-6-carbonitrile 34::thieno[3,2-b]-pyridine-6-carbonitrile 2a

SMILES COc1cc(Nc2c(cnc3cc(sc23)-c2csc(CN3CCN(C)CC3)c2)C#N)c(Cl)cc1Cl

InChI Key InChIKey=XNGKHQGQQBWFHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6088   

LigandPNGBDBM6088(7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-{5-[(4-m...)
Affinity DataIC50: 7.20nMAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2017
Entry Details Article
PubMed
LigandPNGBDBM6088(7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-{5-[(4-m...)
Affinity DataIC50: 7.20nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2005
Entry Details Article
PubMed