BDBM608792 US11701371, Compound 22::US11707471, Compound 22::US20230277570, Compound 22

SMILES COc1ccc2c(ncnc2c1OC)N1CCC(CCP(O)(O)=O)CC1

InChI Key InChIKey=UOEHFUOVYSKBAQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 608792   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM608792(US11701371, Compound 22 | US11707471, Compound 22 ...)
Affinity DataIC50: 500nMAssay Description:Selected compounds of Table 1, Table 2 and other derivatives were prepared and assessed in an ENPP1 activity assay using thymidine monophosphate para...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
Go to US Patent

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM608792(US11701371, Compound 22 | US11707471, Compound 22 ...)
Affinity DataIC50: 500nMAssay Description:ENPP1 activity assay using thymidine monophosphate paranitrophenol (TMP-pNP) as a substrate. Enzyme reactions were prepared with TMP-pNP (2 μM),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Mouse)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM608792(US11701371, Compound 22 | US11707471, Compound 22 ...)
Affinity DataIC50: 500nMAssay Description:Selected compounds of Table 1, Table 2 and other derivatives were prepared and assessed in an ENPP1 activity assay using thymidine monophosphate para...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent