BDBM608712 US11697650, Compound 38::US11697650, Example 21

SMILES Cc1ccc(cc1CN(C(=O)c1cc(-c2cc3OCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccc(O)cc1)C(F)(F)F

InChI Key InChIKey=FIMPGSAXVSAQMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608712   

TargetApoptosis regulator Bcl-2(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM608712(US11697650, Compound 38 | US11697650, Example 21)
Affinity DataIC50: 30nMAssay Description:The following assay concentrations and times were used: 3 ng BCL-2, 5 μl of 1:100 anti-His Tb-labeled donor, 5 μl of 1:100 Dye-labeled acce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2023
Entry Details
Go to US Patent