BDBM608706 US11697650, Compound 5::US11697650, Example 15

SMILES Oc1ccc(cc1)N(Cc1ccccc1C(F)(F)F)C(=O)c1cc(-c2cc3OCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12

InChI Key InChIKey=JZFBZIFJUYXXGO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 608706   

TargetApoptosis regulator Bcl-2(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM608706(US11697650, Compound 5 | US11697650, Example 15)
Affinity DataIC50: 5nMAssay Description:The following assay concentrations and times were used: 3 ng BCL-2, 5 μl of 1:100 anti-His Tb-labeled donor, 5 μl of 1:100 Dye-labeled acce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2023
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM608706(US11697650, Compound 5 | US11697650, Example 15)
Affinity DataIC50: 2.00E+3nMAssay Description:The following assay concentrations and times were used: 10.5 ng BCL-XL, 5 μl of 1:100 anti-His Tb-labeled donor, 5 μl of 1:100 Dye-labeled ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2023
Entry Details
Go to US Patent