BDBM608704 US11697650, Compound 3::US11697650, Example 13

SMILES COc1cccc(CN(C(=O)c2cc(-c3cc4OCOc4cc3C(=O)N3Cc4ccccc4C[C@H]3CN3CCOCC3)n3CCCCc23)c2ccc(O)cc2)c1C

InChI Key InChIKey=VUDKFDDWJADFHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 608704   

TargetApoptosis regulator Bcl-2(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM608704(US11697650, Compound 3 | US11697650, Example 13)
Affinity DataIC50: 5nMAssay Description:The following assay concentrations and times were used: 3 ng BCL-2, 5 μl of 1:100 anti-His Tb-labeled donor, 5 μl of 1:100 Dye-labeled acce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2023
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM608704(US11697650, Compound 3 | US11697650, Example 13)
Affinity DataIC50: 2.00E+3nMAssay Description:The following assay concentrations and times were used: 10.5 ng BCL-XL, 5 μl of 1:100 anti-His Tb-labeled donor, 5 μl of 1:100 Dye-labeled ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2023
Entry Details
Go to US Patent