BDBM60851 US9174940, 18

SMILES CC(=O)N1c2ccc(NC(=O)CCc3ccc(Cl)cc3)cc2C(C)(CC1(C)C)c1ccccc1

InChI Key InChIKey=VUGGLYZVYDRSBE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 60851   

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60851(US9174940, 18)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent