BDBM608430 2-[(4-Amino-cyclohexyl)-methyl- amino]-5-(2,3-dichloro-phenyl)-6- methyl-pyrimidine-4-carboxylic acid amide::US11696916, Compound 32

SMILES CN(C1CCC(N)CC1)c1nc(C)c(-c2cccc(Cl)c2Cl)c(n1)C(N)=O

InChI Key InChIKey=BFVWVCISTNPORU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608430   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Merck Patent

US Patent
LigandPNGBDBM608430(US11696916, Compound 32 | 2-[(4-Amino-cyclohexyl)-...)
Affinity DataIC50: 200nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2023
Entry Details
Go to US Patent