BDBM608411 N-(4-hydroxyphenyl)-N-(4-methylbenzyl)-3-(6-{[(3S)-3-(morpholin-4-ylmethyl)-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}-1,3-benzodioxol-5-yl)-5,6,7,8-tetrahydroindolizine-1-carboxamide::US11697650, Compound 20::US11697650, Example 4

SMILES Cc1ccc(CN(C(=O)c2cc(-c3cc4OCOc4cc3C(=O)N3Cc4ccccc4C[C@H]3CN3CCOCC3)n3CCCCc23)c2ccc(O)cc2)cc1

InChI Key InChIKey=UFQMUOVUWHSCEB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 608411   

TargetApoptosis regulator Bcl-2(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM608411(US11697650, Compound 20 | US11697650, Example 4 | ...)
Affinity DataIC50: 7.5nMAssay Description:The following assay concentrations and times were used: 3 ng BCL-2, 5 μl of 1:100 anti-His Tb-labeled donor, 5 μl of 1:100 Dye-labeled acce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2023
Entry Details
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TargetBcl-2-like protein 1(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM608411(US11697650, Compound 20 | US11697650, Example 4 | ...)
Affinity DataIC50: 3.00E+3nMAssay Description:The following assay concentrations and times were used: 10.5 ng BCL-XL, 5 μl of 1:100 anti-His Tb-labeled donor, 5 μl of 1:100 Dye-labeled ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2023
Entry Details
Go to US Patent