BDBM608370 US11691989, Compound 26::Z)-15-chloro-13,23,61-trimethyl-21-(2- (methylamino)-2-oxoethyl)-11H,21H,61H-10- oxa-4,8-dithia-1(4,1)-indola-2(4,5),6(3,5)- dipyrazola-9(3,1)- naphthalenacyclotridecaphane-12-carboxylic acid

SMILES CNC(=O)Cn1nc(C)c-2c1CSCc1cc(CSc3cc(OCCCn4c(C(O)=O)c(C)c5c-2c(Cl)ccc45)c2ccccc2c3)n(C)n1

InChI Key InChIKey=NGSJRIBQWMAIAG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608370   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Human)
Ascentage Pharma (Suzhou)

US Patent
LigandPNGBDBM608370(US11691989, Compound 26 | Z)-15-chloro-13,23,61-tr...)
Affinity DataIC50: 14nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent