BDBM608343 US11691981, Compound 80::US11691981, Compound 81

SMILES CC(C)(O)c1cc(Nc2cc(Oc3cn(nc3C(=O)Nc3ccccc3F)C3CC3)ccn2)ccn1

InChI Key InChIKey=RILTXKVWKFTVRM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 608343   

TargetTGF-beta receptor type-1(Human)
Inventisbio

US Patent
LigandPNGBDBM608343(US11691981, Compound 80 | US11691981, Compound 81)
Affinity DataIC50: 57nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1(Human)
Inventisbio

US Patent
LigandPNGBDBM608343(US11691981, Compound 80 | US11691981, Compound 81)
Affinity DataIC50: 51nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent