BDBM607517 6-methyl-N-(2-methyl-6- (trifluoromethyl)phenyl)-4-oxo- 1-phenyl-1,4-dihydropyridazine- 3-carboxamide::US11690850, Example 29

SMILES Cc1cccc(c1NC(=O)c1nn(c(C)cc1=O)-c1ccccc1)C(F)(F)F

InChI Key InChIKey=XKAUZTVEUUPXPU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 607517   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University Of Texas

US Patent
LigandPNGBDBM607517(6-methyl-N-(2-methyl-6- (trifluoromethyl)phenyl)-4...)
Affinity DataIC50: 1.15E+3nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent