BDBM607249 US11685745, Example 184

SMILES Clc1cc2nc(oc2c2c1NC(=O)NC21CCCCC1)C(=O)N1C[C@@H]2C[C@H]1CO2

InChI Key InChIKey=JQKIXRIOYFGTGK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 607249   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 607249BDBM607249(US11685745, Example 184)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 607249BDBM607249(US11685745, Example 184)
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent