BDBM607194 US11685745, Example 111

SMILES COC1(C)CN(Cc2nc3cc(Cl)c4NC(=O)NC5(CCCCC5)c4c3o2)C1

InChI Key InChIKey=FIWQVLYLPLDEPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 607194   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 607194BDBM607194(US11685745, Example 111)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 607194BDBM607194(US11685745, Example 111)
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent