BDBM607120 US11685745, Example 433

SMILES CN(C)C1CCN(CC1)C(=O)c1cc2cc(Cl)c3NC(=O)NC4(CCCCC4)c3c2o1

InChI Key InChIKey=XYNNNIHPWICWPJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 607120   

LigandChemical structure of BindingDB Monomer ID 607120BDBM607120(US11685745, Example 433)
Affinity DataIC50: 28nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 607120BDBM607120(US11685745, Example 433)
Affinity DataIC50: 58nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 607120BDBM607120(US11685745, Example 433)
Affinity DataIC50: 1.00E+3nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 607120BDBM607120(US11685745, Example 433)
Affinity DataIC50: 1.00E+3nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent