BDBM605842 US11680056, Example 23A::US11680056, Example 23B

SMILES Cc1cnc(COc2cc(C)n(-c3cc(ncc3C)-c3ccnc(n3)C(C)(C)O)c(=O)c2Cl)c(F)c1

InChI Key InChIKey=RMNVWIVFPWHNGW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 605842   

LigandPNGBDBM605842(US11680056, Example 23A | US11680056, Example 23B)
Affinity DataIC50: 3.16nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
Go to US Patent

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandPNGBDBM605842(US11680056, Example 23A | US11680056, Example 23B)
Affinity DataIC50: 1.26E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
Go to US Patent

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandPNGBDBM605842(US11680056, Example 23A | US11680056, Example 23B)
Affinity DataIC50: 1.00E+4nMAssay Description:This study evaluates the inhibitory potency of invention compound on p38/MK2 pathway vs p38/PRAK pathway. More specially the compound concentration (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
Go to US Patent

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandPNGBDBM605842(US11680056, Example 23A | US11680056, Example 23B)
Affinity DataIC50: 3.16E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
Go to US Patent