BDBM605738 US11680056, Example 4::US11680056, Example 4A::US11680056, Example 4B

SMILES Cc1cnc(cc1-n1c(C)cc(OCc2ncc(F)cc2F)c(Cl)c1=O)-c1ccnc(n1)C(C)(C)CO

InChI Key InChIKey=VWNROJWIQIWFSP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 605738   

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandPNGBDBM605738(US11680056, Example 4 | US11680056, Example 4B | U...)
Affinity DataIC50: 15.8nMAssay Description:This study evaluates the inhibitory potency of invention compound on p38/MK2 pathway vs p38/PRAK pathway. More specially the compound concentration (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
Go to US Patent

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandPNGBDBM605738(US11680056, Example 4 | US11680056, Example 4B | U...)
Affinity DataIC50: 7.94E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
Go to US Patent

LigandPNGBDBM605738(US11680056, Example 4 | US11680056, Example 4B | U...)
Affinity DataIC50: 1.58nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
Go to US Patent

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandPNGBDBM605738(US11680056, Example 4 | US11680056, Example 4B | U...)
Affinity DataIC50: 3.98E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
Go to US Patent

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandPNGBDBM605738(US11680056, Example 4 | US11680056, Example 4B | U...)
Affinity DataIC50: 794nMAssay Description:This study evaluates the inhibitory potency of invention compound on p38/MK2 pathway vs p38/PRAK pathway. More specially the compound concentration (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
Go to US Patent

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandPNGBDBM605738(US11680056, Example 4 | US11680056, Example 4B | U...)
Affinity DataIC50: 3.16E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
Go to US Patent