BDBM605731 US11680056, Example 2

SMILES Cc1cnc(cc1-n1c(C)cc(OCc2ncc(F)cc2F)c(Cl)c1=O)-c1nc(cs1)C(C)(C)O

InChI Key InChIKey=DYJMJUSMUCZTLM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 605731   

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandPNGBDBM605731(US11680056, Example 2)
Affinity DataIC50: 31.6nMAssay Description:This study evaluates the inhibitory potency of invention compound on p38/MK2 pathway vs p38/PRAK pathway. More specially the compound concentration (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
Go to US Patent

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandPNGBDBM605731(US11680056, Example 2)
Affinity DataIC50: 3.98E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
Go to US Patent