BDBM60550 BDBM50448682::US9102669, 53

SMILES Fc1ccc(cc1)-c1ccc(nn1)N1CCC(CC1)N1CCc2ccc(F)cc12

InChI Key InChIKey=UPZYJNDFFUPCMP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 60550   

TargetAcyl-CoA desaturase 1(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM60550(US9102669, 53 | BDBM50448682)
Affinity DataIC50: 777nMT: 2°CAssay Description:The SCD1 enzymatic assay was done in a volume of 50 μL using 10 μg of RLM (prepared as described above) in a 96-well polypropylene plate (e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2016
Entry Details
Go to US Patent

TargetAcyl-CoA desaturase 1(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM60550(US9102669, 53 | BDBM50448682)
Affinity DataIC50: 6nMT: 2°CAssay Description:The SCD1 enzymatic assay was done in a volume of 50 μL using 10 μg of RLM (prepared as described above) in a 96-well polypropylene plate (e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2016
Entry Details
Go to US Patent

TargetAcyl-CoA desaturase 1(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM60550(US9102669, 53 | BDBM50448682)
Affinity DataIC50: 19nMT: 2°CAssay Description:The SCD1 enzymatic assay was done in a volume of 50 μL using 10 μg of RLM (prepared as described above) in a 96-well polypropylene plate (e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2016
Entry Details
Go to US Patent

TargetAcyl-CoA desaturase 1(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM60550(US9102669, 53 | BDBM50448682)
Affinity DataIC50: 777nMAssay Description:Inhibition of SCD1 in Sprague-Dawley rat liver microsomes using stearoyl-[9,10-3H]-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed