BDBM605442 N-(2-chloro-5-(3-cyano-4-((1R- phenylethyl)amino)quinolin-6-yl)pyridin- 3-yl)methanesulfonamide::US11673876, Compound 48R

SMILES C[C@@H](Nc1c(cnc2ccc(cc12)-c1cnc(Cl)c(NS(C)(=O)=O)c1)C#N)c1ccccc1

InChI Key InChIKey=RQUAEMCWWIFVCJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 605442   

LigandPNGBDBM605442(N-(2-chloro-5-(3-cyano-4-((1R- phenylethyl)amino)q...)
Affinity DataIC50: 11nMAssay Description:Z′-LYTE Assay Conditions: Test Compounds: The Test Compounds are screened in 1% DMSO (final) in the well. For 10 point titrations, 3-fold seria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2023
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Mekanistic Therapeutics

US Patent
LigandPNGBDBM605442(N-(2-chloro-5-(3-cyano-4-((1R- phenylethyl)amino)q...)
Affinity DataIC50: 11nMAssay Description:Z′-LYTE Assay Conditions: Test Compounds: The Test Compounds are screened in 1% DMSO (final) in the well. For 10 point titrations, 3-fold seria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2023
Entry Details
Go to US Patent