BDBM605435 US11672788, Compound GNTbm-12

SMILES Cc1ccc(\C=C\CC(=O)Nc2ccc(nc2)C(=O)Nc2ccc(cc2N)C(F)(F)F)cn1

InChI Key InChIKey=OICCBDUGYWYXAN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 605435   

TargetHistone deacetylase 1(Human)
Great Novel Therapeutics Biotech & Medicals

US Patent
LigandPNGBDBM605435(US11672788, Compound GNTbm-12)
Affinity DataIC50: 2.00E+4nMAssay Description:HDACs assay was performed according to standard Protocols (Fluorgenic HDACs 1, 2, and 3 assay kit, BPS Bioscience ). All of the compounds, with Chida...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Great Novel Therapeutics Biotech & Medicals

US Patent
LigandPNGBDBM605435(US11672788, Compound GNTbm-12)
Affinity DataIC50: 2.00E+4nMAssay Description:HDACs assay was performed according to standard Protocols (Fluorgenic HDACs 1, 2, and 3 assay kit, BPS Bioscience ). All of the compounds, with Chida...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Great Novel Therapeutics Biotech & Medicals

US Patent
LigandPNGBDBM605435(US11672788, Compound GNTbm-12)
Affinity DataIC50: 2.00E+4nMAssay Description:HDACs assay was performed according to standard Protocols (Fluorgenic HDACs 1, 2, and 3 assay kit, BPS Bioscience ). All of the compounds, with Chida...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
Go to US Patent