BDBM605430 US11672788, Compound GNTbm-04

SMILES Nc1cc(F)ccc1NC(=O)c1ccc(NC(=O)C\C=C\c2cccnc2)cn1

InChI Key InChIKey=ZEWGQCOCULACFM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 605430   

TargetHistone deacetylase 1(Human)
Great Novel Therapeutics Biotech & Medicals

US Patent
LigandPNGBDBM605430(US11672788, Compound GNTbm-04)
Affinity DataIC50: 380nMAssay Description:HDACs assay was performed according to standard Protocols (Fluorgenic HDACs 1, 2, and 3 assay kit, BPS Bioscience ). All of the compounds, with Chida...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Great Novel Therapeutics Biotech & Medicals

US Patent
LigandPNGBDBM605430(US11672788, Compound GNTbm-04)
Affinity DataIC50: 540nMAssay Description:HDACs assay was performed according to standard Protocols (Fluorgenic HDACs 1, 2, and 3 assay kit, BPS Bioscience ). All of the compounds, with Chida...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Great Novel Therapeutics Biotech & Medicals

US Patent
LigandPNGBDBM605430(US11672788, Compound GNTbm-04)
Affinity DataIC50: 200nMAssay Description:HDACs assay was performed according to standard Protocols (Fluorgenic HDACs 1, 2, and 3 assay kit, BPS Bioscience ). All of the compounds, with Chida...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
Go to US Patent