BDBM605424 US11672785, Compound C::US20250114338, Example 156

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(C)(C)F)c1ccc(OCCN2CC(CF)C2)cc1

InChI Key InChIKey=IPBQTKXTHVMANC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 605424   

TargetEstrogen receptor(Human)
Olema Pharmaceuticals

US Patent
LigandPNGBDBM605424(US11672785, Compound C | US20250114338, Example 15...)
Affinity DataIC50: 1.35nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
Go to US Patent

TargetEstrogen receptor(Human)
Olema Pharmaceuticals

US Patent
LigandPNGBDBM605424(US11672785, Compound C | US20250114338, Example 15...)
Affinity DataEC50:  0.335nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent