BDBM605421 US11672785, Compound B::US20240131013, Compound B

SMILES CCCN1CC(C1)Oc2ccc(cc2)[C@@H]3c4c(c5ccccc5[nH]4)C[C@H](N3CC(C)(C)F)C

InChI Key InChIKey=LBSFUBLFDCAEKV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 605421   

TargetEstrogen receptor(Human)
Olema Pharmaceuticals

US Patent
LigandPNGBDBM605421(US11672785, Compound B | US20240131013, Compound B)
Affinity DataIC50: 2.69nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
Go to US Patent

TargetSteroid hormone receptor ERR1(Human)
Olema Pharmaceuticals

US Patent
LigandPNGBDBM605421(US11672785, Compound B | US20240131013, Compound B)
Affinity DataIC50: 2.69nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERα ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent