BDBM604843 7-[(5R,7R,8R,12aR,14R,15R,15aR,16R)-14-(6- amino-9H-purin-9-yl)-15-fluoro-16-hydroxy- 2,10-dioxido-2,10-disulfanyloctahydro-12H-5,8- methanofuro[3,2-l] [1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecin- 7-yl]-5-chloro-3,7-dihydro-4H-pyrrolo[2,3- d]pyrimidin-4-one di-triethylamine salt::US11666594, Example 26 (optical isomer 1)

SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP(S)(=O)O[C@@H]3[C@H](O)[C@@H](CO[P@@](S)(=O)O[C@H]2[C@H]1F)O[C@H]3n1cc(Cl)c2c1nc[nH]c2=O

InChI Key InChIKey=FHNOHJZPITVLCA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 604843   

TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM604843(7-[(5R,7R,8R,12aR,14R,15R,15aR,16R)-14-(6- amino-9...)
Affinity DataIC50: 530nMAssay Description:The above-mentioned biotinylated STING protein (wild-type (WT)) was prepared by the following method. The culture solution was centrifuged, the obtai...More data for this Ligand-Target Pair
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Date in BDB:
7/9/2023
Entry Details
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