BDBM604690 (S)-(1-(2-((5-(3,4,5-trimethoxyphenyl)pyridin-2-yl)amino)quinazolin-4-yl)pyrrolidin-2-yl)methanol::US11661426, Compound 357d

SMILES COc1cc(cc(OC)c1OC)-c1ccc(Nc2nc(N3CCC[C@H]3CO)c3ccccc3n2)nc1

InChI Key InChIKey=PJMPURWYWSICTI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 604690   

TargetActivin receptor type-1(Human)
Biocryst Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 604690BDBM604690(US11661426, Compound 357d | (S)-(1-(2-((5-(3,4,5-t...)
Affinity DataIC50: 1.00E+3nMAssay Description:Biochemical assays to measure the inhibitory effects of the compounds were performed by ThermoFisher Scientific (Life Technologies). ALK2 inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2023
Entry Details
US Patent