BDBM604672 ((1S,2S,5R)-3-(2-((1-(3,4,5-trimethoxyphenyl)-1H-imidazol-4-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-4-yl)-3-azabicyclo[3.1.0]hexan-2-yl)methanol::US11661426, Compound 332b

SMILES COc1cc(cc(OC)c1OC)-n1cnc(Nc2nc(N3C[C@@H]4C[C@@H]4[C@H]3CO)c3cccn3n2)c1

InChI Key InChIKey=JRLFESVVMAOOAW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 604672   

TargetActivin receptor type-1(Human)
Biocryst Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 604672BDBM604672(US11661426, Compound 332b | ((1S,2S,5R)-3-(2-((1-(...)
Affinity DataIC50: 100nMAssay Description:Biochemical assays to measure the inhibitory effects of the compounds were performed by ThermoFisher Scientific (Life Technologies). ALK2 inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2023
Entry Details
US Patent