BDBM604398 (S)-(1-(4-((1-(3,4,5-trimethoxyphenyl)-1H-imidazol-4-yl)amino)thieno[3,2-d]pyrimidin-2-yl)pyrrolidin-2-yl)methanol::US11661426, Compound 75b

SMILES COc1cc(cc(OC)c1OC)-n1cnc(Nc2nc(nc3ccsc23)N2CCC[C@H]2CO)c1

InChI Key InChIKey=FZWKVHQKWIPJFA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 604398   

TargetActivin receptor type-1(Human)
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM604398(US11661426, Compound 75b | (S)-(1-(4-((1-(3,4,5-tr...)
Affinity DataIC50: 100nMAssay Description:Biochemical assays to measure the inhibitory effects of the compounds were performed by ThermoFisher Scientific (Life Technologies). ALK2 inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2023
Entry Details
Go to US Patent