BDBM60433 BDBM103466::US8552004, 2.01

SMILES C[C@@H]1COCCN1c1cc(nc(n1)-c1ccnc2[nH]ccc12)C1(CC1)[S@@](C)(=N)=O

InChI Key InChIKey=OHUHVTCQTUDPIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 60433   

TargetSerine/threonine-protein kinase ATR(Human)
Astrazeneca

US Patent
LigandPNGBDBM60433(US8552004, 2.01 | BDBM103466)
Affinity DataIC50: 236nMAssay Description:ATM and ATR have distinct and overlapping responses to DNA damage. They must participate together and responses must be co-ordinated. Both pathways...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Astrazeneca

US Patent
LigandPNGBDBM60433(US8552004, 2.01 | BDBM103466)
Affinity DataIC50: 240nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed