BDBM604239 (3R,5R)-N-{6,7-dimethoxy- 1H,2H,3H-cyclopenta[b]quinolin-9- yl}-5-fluoropiperidin-3-amine::US11661410, No. 416

SMILES COc1cc2nc3CCCc3c(N[C@H]3CNC[C@H](F)C3)c2cc1OC

InChI Key InChIKey=BRWFPHISLZWENR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 604239   

TargetHistone-lysine N-methyltransferase EHMT2(Human)
Global Blood Therapeutics

US Patent
LigandPNGBDBM604239(US11661410, No. 416 | (3R,5R)-N-{6,7-dimethoxy- 1H...)
Affinity DataIC50: 126nMAssay Description:For the assay, the following buffer was used to set up reactions: 50 mM Tris-HCl pH9, 50 mM NaCl, 0.01% Tween-20 and 1 mM DTT (added fresh prior to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
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