BDBM604230 (3R)-N-{6-ethoxy-7-methoxy- 1H,2H,3H-cyclopenta[b]quinolin-9- yl}piperidin-3-amine::US11661410, No. 407

SMILES CCOc1cc2nc3CCCc3c(N[C@@H]3CCCNC3)c2cc1OC

InChI Key InChIKey=VDALPDZWHZCKCS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 604230   

TargetHistone-lysine N-methyltransferase EHMT2(Human)
Global Blood Therapeutics

US Patent
LigandPNGBDBM604230(US11661410, No. 407 | (3R)-N-{6-ethoxy-7-methoxy- ...)
Affinity DataIC50: 100nMAssay Description:For the assay, the following buffer was used to set up reactions: 50 mM Tris-HCl pH9, 50 mM NaCl, 0.01% Tween-20 and 1 mM DTT (added fresh prior to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
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