BDBM604219 N-[2,3-dimethoxy-6H,7H,8H- cyclopenta[b]1,5-naphthyridin-9-yl]- 1-(propan-2-yl)piperidin-4-amine::US11661410, No. 134

SMILES COc1cc2nc3CCCc3c(NC3CCN(CC3)C(C)C)c2nc1OC

InChI Key InChIKey=DGGSJFAZDTVHIQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 604219   

TargetHistone-lysine N-methyltransferase EHMT2(Human)
Global Blood Therapeutics

US Patent
LigandPNGBDBM604219(US11661410, No. 134 | N-[2,3-dimethoxy-6H,7H,8H- c...)
Affinity DataIC50: 158nMAssay Description:For the assay, the following buffer was used to set up reactions: 50 mM Tris-HCl pH9, 50 mM NaCl, 0.01% Tween-20 and 1 mM DTT (added fresh prior to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
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