BDBM604161 N-{6,7-dimethoxy-1H,2H,3H-cyclopenta[b]quinolin-9-yl}-1-(2-fluorophenyl)piperidin-4-amine hydrochloride::US11661410, No. 16

SMILES COc1cc2nc3CCCc3c(NC3CCN(CC3)C3CCOCC3)c2cc1OC

InChI Key InChIKey=NDOLDOAAUXRZBR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 604161   

TargetHistone-lysine N-methyltransferase EHMT2(Human)
Global Blood Therapeutics

US Patent
LigandPNGBDBM604161(US11661410, No. 16 | N-{6,7-dimethoxy-1H,2H,3H-cyc...)
Affinity DataIC50: 53.7nMAssay Description:For the assay, the following buffer was used to set up reactions: 50 mM Tris-HCl pH9, 50 mM NaCl, 0.01% Tween-20 and 1 mM DTT (added fresh prior to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
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