BDBM604066 US11660293, Example 174

SMILES CCOc1ccc(C)nc1C(=O)N1C2CC(C2)[C@@H](C)C1CNc1nc2ccc(F)cc2s1

InChI Key InChIKey=PETFZHTTWWEOOY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 604066   

TargetOrexin/Hypocretin receptor type 1(Human)
Chronos Therapeutics

US Patent
LigandPNGBDBM604066(US11660293, Example 174)
Affinity DataKi:  1.51nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
Chronos Therapeutics

US Patent
LigandPNGBDBM604066(US11660293, Example 174)
Affinity DataKi:  87.1nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
Go to US Patent