BDBM604062 US11660293, Example 168::US11660293, Example 170

SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccc(F)cc2s1)C(=O)c1cc(F)ccc1-n1nccn1

InChI Key InChIKey=QTDGTVJGEPWMKX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 604062   

TargetOrexin/Hypocretin receptor type 1(Human)
Chronos Therapeutics

US Patent
LigandPNGBDBM604062(US11660293, Example 168 | US11660293, Example 170)
Affinity DataKi:  1.38nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
Go to US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Chronos Therapeutics

US Patent
LigandPNGBDBM604062(US11660293, Example 168 | US11660293, Example 170)
Affinity DataKi:  3.47nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
Chronos Therapeutics

US Patent
LigandPNGBDBM604062(US11660293, Example 168 | US11660293, Example 170)
Affinity DataKi:  1.02E+3nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
Chronos Therapeutics

US Patent
LigandPNGBDBM604062(US11660293, Example 168 | US11660293, Example 170)
Affinity DataKi:  1.32E+3nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
Go to US Patent